Studies on antivenom activity of Andrographis paniculata and Aristolochia indica plant extracts against Daboia russelli venom by in vivo and in vitro methods

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Studies on Antivenom Activity of Aristolochia indica Plant Extract Against Red Scorpion Venom by in Vivo and in Vitro Methods

Objective: Mesobuthus tumulus is the most lethal among all poisonous species of scorpion. Aristolochia indica is one of the plants which have long been used in traditional herbal medicine for the treatment of poisoning by animal bites. Hence the study was planned to evaluate the ethanolic extract of Aristolochia indica for the treatment of Mesobuthus tamulus envenoming. Materials and Methods: C...

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Inhibition of Toxic Effects of Viper and Cobra Venom by Indian Medicinal Plants

The mortality rate from snakebites in West Bengal is very high and most of the deaths are caused by the Daboia russelli and Naja naja envenomation. Twenty-three plants from the seventeen families were collected from the traditional healers and explored for the first time for antisnake venom activity. In our previous report, the methanolic root extract of the Indian medicinal plants Pluchea indi...

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In Vivo and In Vitro Studies on Neutralizing Effects of Acorus calamus and Withania somnifera root extracts against Echis carinatus venom

Neutralization effects of Acorus calamus and Withania somnifera root extracts were tested against Echis carinatus venom. Both plant extracts were effectively neutralized the various pharmacological activities induced by Echis carinatus venom. About 0.14 mg of Acorus calamus and 0.16 mg of Withania somnifera root extracts were able to completely neutralize the lethal a...

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Antitoxin activity of Mucuna pruriens aqueous extracts against Cobra and Krait venom by in vivo and in vitro methods

Aqueous extracts of Mucuna pruriens seeds were tested for their activity on various pharmacological effects like lethality, phospholipase activity, edema forming activity, fibrinolytic activity and haemorrhagic activity of of cobra and krait venoms. The aqueous extract displayed a significant inhibitory effect on the lethality, phospholipase activity, edema forming activity, fibrinolytic activi...

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An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure andrographolide

BACKGROUND The anti-inflammatory activity of Andrographis paniculata (Acanthaceae), a traditional medicine widely used in Asia, is commonly attributed to andrographolide, its main secondary metabolite. Commercial A. paniculata extracts are standardised to andrographolide content. We undertook the present study to investigate 1) how selective enrichment of andrographolide in commercial A. panicu...

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ژورنال

عنوان ژورنال: Indian Journal of Science and Technology

سال: 2009

ISSN: 0974-6846,0974-5645

DOI: 10.17485/ijst/2009/v2i4.9